Using this method, they found that a combination of failures—from the partial loss of an essential protein to weakened connections between chromosomes—can cause errors that increase with maternal age.

Women age differently from men when it comes to health—particularly in conditions like cardiovascular disease and neurodegenerative disorders such as dementia and Parkinson's. Unlike men, who carry ...

JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...

hat: Researchers have identified inherited genetic variants that may predict the loss of one copy of a woman’s two X chromosomes as she ages, a phenomenon known as mosaic loss of chromosome X, or mLOX ...

Sex chromosome abnormalities in horses encompass a range of conditions that compromise fertility, development and early gestation. The most prevalent anomalies include X-monosomy (Turner syndrome), 65 ...

A new study led by NYU Langone Health researchers found that cancer cells are better able to resist treatments when they have an abnormal number of chromosomes, which are DNA strands wound up in ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply — and can contribute to infertility, pregnancy loss, and ...